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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SDK1
All Species:
14.24
Human Site:
S561
Identified Species:
24.1
UniProt:
Q7Z5N4
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z5N4
NP_689957.3
2213
242076
S561
Y
A
A
N
T
E
G
S
L
N
A
S
A
T
L
Chimpanzee
Pan troglodytes
XP_518946
2168
238269
A521
E
G
S
L
N
A
S
A
T
L
T
V
W
N
R
Rhesus Macaque
Macaca mulatta
XP_001105243
2118
232418
S505
Y
A
A
N
T
E
G
S
L
N
A
S
A
T
L
Dog
Lupus familis
XP_547004
2144
235913
T524
R
V
V
I
K
G
T
T
A
T
L
R
C
G
A
Cat
Felis silvestris
Mouse
Mus musculus
Q3UH53
2193
240287
S543
Y
A
A
N
T
E
A
S
V
N
A
S
A
M
L
Rat
Rattus norvegicus
XP_001073292
2181
239558
S531
Y
A
T
N
T
E
A
S
V
N
A
S
A
M
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513017
2131
235273
I521
T
H
D
P
R
I
S
I
R
Y
F
W
K
K
D
Chicken
Gallus gallus
Q8AV58
2169
239459
T521
L
N
A
F
V
M
L
T
V
W
N
R
T
F
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_686686
2126
234665
R517
H
D
P
R
V
G
V
R
Y
V
W
K
K
D
E
Tiger Blowfish
Takifugu rubipres
Q98902
1277
141937
Fruit Fly
Dros. melanogaster
O97394
2224
246236
I548
S
V
L
V
R
T
Q
I
I
Q
P
P
V
D
T
Honey Bee
Apis mellifera
XP_623565
2176
242722
Q522
L
V
R
T
Q
I
I
Q
P
P
V
D
T
S
V
Nematode Worm
Caenorhab. elegans
Q9N3X8
2325
259146
S547
N
V
Q
V
N
G
D
S
L
I
E
Y
G
P
A
Sea Urchin
Strong. purpuratus
XP_781559
2931
322437
L558
T
C
I
A
T
N
T
L
N
T
A
N
S
S
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.7
91.5
86.7
N.A.
89.7
87.3
N.A.
79.6
78.9
N.A.
66
20.5
36.3
36.3
26.1
20.7
Protein Similarity:
100
96.1
93
91.5
N.A.
94
92
N.A.
87.8
87.8
N.A.
79.8
33.5
53.5
53.5
43.8
37.1
P-Site Identity:
100
0
100
0
N.A.
80
73.3
N.A.
0
6.6
N.A.
0
0
0
0
13.3
13.3
P-Site Similarity:
100
13.3
100
6.6
N.A.
86.6
80
N.A.
0
26.6
N.A.
6.6
0
6.6
13.3
13.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
29
29
8
0
8
15
8
8
0
36
0
29
0
22
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
8
8
0
0
0
8
0
0
0
0
8
0
15
8
% D
% Glu:
8
0
0
0
0
29
0
0
0
0
8
0
0
0
8
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
8
0
0
8
0
% F
% Gly:
0
8
0
0
0
22
15
0
0
0
0
0
8
8
0
% G
% His:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
8
0
15
8
15
8
8
0
0
0
0
8
% I
% Lys:
0
0
0
0
8
0
0
0
0
0
0
8
15
8
0
% K
% Leu:
15
0
8
8
0
0
8
8
22
8
8
0
0
0
29
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
15
0
% M
% Asn:
8
8
0
29
15
8
0
0
8
29
8
8
0
8
0
% N
% Pro:
0
0
8
8
0
0
0
0
8
8
8
8
0
8
0
% P
% Gln:
0
0
8
0
8
0
8
8
0
8
0
0
0
0
0
% Q
% Arg:
8
0
8
8
15
0
0
8
8
0
0
15
0
0
8
% R
% Ser:
8
0
8
0
0
0
15
36
0
0
0
29
8
15
0
% S
% Thr:
15
0
8
8
36
8
15
15
8
15
8
0
15
15
8
% T
% Val:
0
29
8
15
15
0
8
0
22
8
8
8
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
8
8
8
0
0
% W
% Tyr:
29
0
0
0
0
0
0
0
8
8
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _